Challenges in Pharmacogenomic Testing
نویسندگان
چکیده
منابع مشابه
Psychiatric pharmacogenomic testing in clinical practice
The clinical adoption of psychiatric pharmacogenomic testing has taken place rapidly over the past 7 years. Initially, drug-metabolizing enzyme genes, such as the cytochrome P450 2D6 gene (CYP2D6), were identified. Genotyping the highly variable cytochrome P450 2D6 gene now provides clinicians with the opportunity to identify both poor metabolizers and ultrarapid metabolizers of 2D6 substrate m...
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This review evaluates the utilization of pharmacogenomic testing to guide treatment with antipsychotic medications as well as the evidence supporting the use of pharmacogenomic testing. There are two basic objectives for using pharmacogenomic testing. The first pharmacogenomic objective is to minimize adverse effects. The second pharmacogenomic objective is to improve clinical outcomes. While a...
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ژورنال
عنوان ژورنال: AACR Education book
سال: 2008
ISSN: 1943-6475
DOI: 10.1158/aacr.edb-08-8072